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KMID : 0368820110500050347
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Journal of the Korean Neuropsychiatr Association
2011 Volume.50 No. 5 p.347 ~ p.353
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Pathogenesis of Post-Stroke Depression : A Bio-Psycho-Social Integrative Model
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Kang Hee-Ju
Kim Sung-Wan
Kim Jae-Min
Shin Il-Seon
Yoon Jin-Sang
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Abstract
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Depression is common after a stroke and has adverse effects on both the course and prognosis. A proper understanding on the pathogenetic mechanisms of post-stroke depression (PSD) is the first step in the treatment of PSD. PSD should not be considered a purely organic neurological mood syndrome but rather the consequence of a complex interaction model of biological, psychological, and social factors. Based on the pathogenesis, a bio-psycho-social approach is mandatory in the treatment of PSD. A medical team with an integrative bio-psycho-social view should take a pivotal role in the management of PSD.
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KEYWORD
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Post-stroke depression, Pathogenesis, Treatment, Bio-psycho-social model
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